Strengthen clinical decision-making with capnography – CapnoAcademy CapnoAcademy

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Editor’s note: Capnography is one of the most powerful tools in the EMS toolbox. It tells us what’s happening with a patient’s ventilation, perfusion and metabolism — instantly and continuously. But to use it effectively, you have to understand what the waveforms are telling you. Learn how to decode capnography with our Infographic: Understanding normal and abnormal capnography waveforms

Medical professionals agree that capnography is an important non-invasive, low-risk tool for treating and monitoring patients, but it should always be interpreted alongside the patient’s overall clinical picture, vital signs and other assessment data to make informed decisions.

| MORE: Infographic: Understanding normal and abnormal capnography waveforms

“Capnography gives different information that can paint a more detailed clinical picture, especially in conjunction with other vital sign markers such as SpO2,” noted Dr. Maria Mulligan-Buckmiller, MD, a Johns Hopkins University EMS fellow. “It can also be a more sensitive and timely indication of worsening status, for example, in hypoxia resulting from inadequate respirations or even apnea, the end tidal will likely become abnormal more promptly than the SpO2.”

“When you look at end-tidal, you’re seeing the exhaust from cellular respiration,” noted Dr. Rishi Kundi, chief of vascular and endovascular trauma surgery at the R Adams Cowley Shock Trauma Center on the campus of the University of Maryland Medical Center in Baltimore and medical director for Maryland’s Go-Team. “End-tidal depends on oxygen delivery to tissues through arterial perfusion, aerobic cellular respiration throughout the body, delivery of CO2 to the venous system, delivery of venous blood to the heart and ventilation.”

“A low end-tidal means, among other things, you’re not perfusing well. You’re not producing normal levels of CO2 because you’re not delivering normal levels of oxygen to the tissues,” Kundi added. “Poor perfusion manifests in the prehospital context primarily as cold and pale, potentially mottled extremities and unresponsiveness. Ultimately, poor perfusion is accompanied by an absence of the usual signs of life.”

According to Mulligan-Buckmiller, who works at the Johns Hopkins Howard County Medical Center in Columbia, Maryland and is involved in the medical direction of Howard County(Maryland) Fire and Rescue Services, the uses for capnography have greatly expanded in recent years, including assessing:

  • Adequate respirations
  • Endotracheal tube placement
  • Response and effectiveness of mechanical ventilation
  • Achievement of return of spontaneous circulation (ROSC)
  • Cerebral vasoconstriction/vasodilation in head trauma
  • Perfusion status in both trauma and shock situations

Identifying shock with capnography

In shock, capnography is a critical, non-invasive tool that provides real-time data on tissue perfusion and ventilation by continually monitoring the patient’s end-tidal CO2 (EtCO2), the CO2 level in exhaled air. A decrease in EtCO2 can signal worsening shock due to reduced blood flow and tissue perfusion. A normal range should be 35-45 mmHg for adults; levels below that in a shock patient indicate significant distress and the need for aggressive management.

“In shock, an end tidal 10mmHg) than the PCO2 level, causing increased hypercarbia and resulting acidosis in patients in shock. This underlines the point that while end tidal can be a helpful marker of changing status, improving perfusion it should not be taken as a reliable indicator of the true acid-base status of the patient alone,” Mulligan-Buckmiller said. “Other studies have shown that this discordance will only increase as shock progresses, underlining the point that the end tidal should be seen as additional data that should not take priority over the holistic clinical picture of the patient.”

Lawner added, “it is more about augmenting perfusion than improving EtC02. Patients who are significantly acidotic may exhibit rapid breathing to compensate. Respiratory compensation lowers the level of EtC02 and may not need to be immediately corrected depending upon the treatment scenario.”

| MORE: Capnography: A vital sign for every EMS patient

Pre-hospital and interfacility transfer capnography considerations

“Capnography is mandatory for intubated patients and is used to monitor patient perfusion while enroute to definitive care. Existing prehospital and interfacility transport protocols suggest that values can inform treatment strategies for patients experiencing shock and respiratory related emergencies,” Lawner said.

“Capnography is a unique modality in that it is a surrogate marker for patient perfusion,” Lawner said. “It is a continuous variable that can be ‘trended’ and therefore provides information about responses to treatment.”

Additional uses for capnography in EMS

In the prehospital setting, capnography can be used for:

  • Confirming endotracheal tube placement. Capnography provides an objective measurement of exhaled carbon dioxide (CO2), which helps verify that an ET tube is correctly placed in the trachea and not the esophagus.
    • This is crucial during intubation to ensure proper oxygenation and ventilation.
  • Monitoring CPR quality. Capnography can be used to assess the effectiveness of chest compressions during CPR by measuring the level of CO2 in exhaled air.
    • A sudden increase in CO2 levels can indicate (ROSC).
    • It can also help identify inadequate chest compressions, prompting adjustments to improve CPR quality.
  • Assessing respiratory and circulatory status. Capnography can help detect changes in patient’s ventilation, perfusion and metabolism by monitoring CO2 levels.
    • Changes in the CO2 waveform can indicate issues like airway obstruction, pulmonary embolism or inadequate tissue perfusion.
    • This information allows clinicians to make informed decisions about treatment and patient management.
  • Additional capnography medical monitoring uses. Capnography is a valuable tool for monitoring patients with various conditions, including respiratory distress, shock and opioid overdose.
    • Uses include both intubated and spontaneously breathing patients.

Lawner suggested when applying EtCO2 values to an individual clinical scenario, consider asking focused, closed ended questions:

  • Is the endotracheal tube still in place?
  • Is the patient in shock or is there evidence of low perfusion?
  • Is there evidence of severe obstructive disease (e.g., asthma)?

Mulligan-Buckmiller emphasized, “capnography should be used in all patients with concern for respiratory impairment, in all patients with supraglottic or endotracheal airways, all patients on mechanical ventilation, all patients who received sedation/medication that could impair respiratory status, patients with head trauma (especially in head bleeds), patients in cardiac arrest and shock.”

“Within the Maryland EMS system, EtC02 is an ALS skill. Typically, ALS clinicians have access to end tidal equipment. Speaking for systems that I am directly involved with, all ALS transport and critical care ambulances/helicopters can monitor capnography,” Lawner said. “I think it is important to look at how BLS clinicians can utilize this important technology. For example, end tidal waveforms can confirm an adequately placed supraglottic airway.”

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